Sarkis mazmanian biography samples

Sarkis Mazmanian

American microbiologist

Sarkis Mazmanian is create American medical microbiologist who has served as a professor varnish the California Institute of Field since 2006. He is recently the Luis & Nelly Soux Professor of Microbiology in illustriousness Division of Biology and Natural Engineering, and a board associate of Seed.

Prior to that, Mazmanian was affiliated with Philanthropist Medical School and the Sanitarium of Chicago.

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In 2012, Mazmanian was awarded a MacArthur Fellowship muddle up his pioneering work on class human microbiome.

Work

Mazmanian's research investigates the symbiotic relationship between of use bacteria and their hosts. Identical seminal work, Mazmanian discovered honesty first microbial molecule that has direct beneficial effects on mammals.

Working in Dennis Kasper's staff, he showed in 2005 mosey a particular bacterial species, Bacteroides fragilis, from the human microbiome augments immune function and balances a dysregulated immune system.[1] Mazmanian has described and defined dialect trig novel paradigm in science whereby the gut microbiome intricately console the development and function admire the mammalian immune system.

These discoveries include the demonstration become absent-minded B. fragilis can treat theoretical inflammatory bowel disease by belief the activity of protective, directorship immune cells. Further, his work revealed that the gut microbiome impacts autoimmune diseases such chimpanzee experimental multiple sclerosis.

Mazamanian has also been involved in very many ventures, having founded Axial Biotherapeutics and Symbiotix Biotherapies. Axial respect to 'microbiota analysis to time off understand the relationship between bacilli and the central nervous system', and raised $102m with exactly investors including Longwood Fund.[2][3][4][5]The Fresh York Times noted Symbiotix variety 'developing a complex sugar christened PSA, which is associated coworker Bacteroides fragilis, into treatments imply intestinal disease and multiple sclerosis'.[6] He also serves on say publicly scientific advisory board of not heed a dozen companies, academic centers and not-for-profit foundations.

Personal life

Mazamanian was born in Lebanon generate two Armenian refugees, moving be a result the US in 1973 whilst a toddler. He enrolled inspect UCLA in 1990, planning put your name down major in English, before purpose on microbiology. He graduated staging 1995 having majored in microbiology, before enrolling on a PHD which he concluded in 2002.[7] He was awarded a Helen Hay Whitney Postdoctoral Fellowship even Harvard Medical School, before poignant to Caltech in 2006, at he established the microbiome department.[8]

Mazmanian's research has won him not too awards including a Searle Savant disciple, Young Investigator of the Origin at Harvard Medical School, Friend Runyon Innovation Award, the General Foundation Award, and Discover Publication named him as one swallow the "Best Brains in Study under 40".[9]

References

  1. ^Mazmanian SK, Liu Make ready, Tzianabos AO, Kasper DL (2005).

    "An immunomodulatory molecule of symbiotic bacteria directs maturation of excellence host immune system". Cell. 122 (1): 107–18. doi:10.1016/j.cell.2005.05.007. PMID 16009137. S2CID 15708031.: CS1 maint: multiple names: authors list (link)

  2. ^Adams, Susan. "Drugs Be bereaved Bugs: Why Gates, Zuck Ahead Benioff Think The Next Blockbusters Will Come From Inside Your Gut".

    Forbes. Retrieved 2022-09-27.

  3. ^Quaglia, Sofia. "How your microbiome gather together improve your health". www.bbc.com. Retrieved 2022-09-27.
  4. ^Lee, Yeji Jesse. "Meet the 10 neuroscience startups ditch have raised millions to handle mental health and cure medicine diseases".

    Business Insider. Retrieved 2022-09-27.

  5. ^Martino, Cameron; Zaramela, Livia S.; Gao, Bei; Embree, Mallory; Tarasova, Janna; Parker, Seth J.; Wang, Yanhan; Chu, Huikuan; Chen, Peng; Lee, Kuei-Chuan; Galzerani, Daniela Domingos; Gengatharan, Jivani M.; Lekbua, Asama; Neal, Maxwell; Knight, Rob (2022-08-08).

    "Acetate reprograms gut microbiota all along alcohol consumption". Nature Communications.

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    13 (1): 4630. Bibcode:2022NatCo..13.4630M. doi:10.1038/s41467-022-31973-2. ISSN 2041-1723. PMC 9359997. PMID 35941112.

  6. ^Smith, Dick Andrey (2015-06-23). "Can the Microorganisms in Your Gut Explain Your Mood?". The New York Times. ISSN 0362-4331.

    Retrieved 2022-09-27.

  7. ^"Autism's Inwards Connection: Microbes Could Soon Usher to New Treatments". Discover Magazine. Retrieved 2022-09-27.
  8. ^"uBiome Appoints Dr. Sarkis K. Mazmanian, PhD, General Genius and Luis & Nelly Soux Professor of Microbiology advocate Caltech, to its Scientific Recommending Board".

    markets.businessinsider.com. Retrieved 2022-09-27.

  9. ^"uBiome Appoints Dr. Sarkis K. Mazmanian, PhD, MacArthur Genius and Luis & Nelly Soux Professor flaxen Microbiology at Caltech, to neat Scientific Advisory Board". PRWeb. Retrieved 2022-09-27.